Davide Seruggia

Davide Seruggia is an Instructor in Pediatrics at Harvard Medical School. He obtained a degree in Biotechnology at the Università di Milano-Bicocca, Italy in 2010, and a PhD in Molecular Biology at the CNB-CSIC in Madrid, Spain in 2014. During his PhD, he focused on non-coding DNA regulatory sequences of pigmentation genes, and generated mice carrying deletions of selected enhancers. Analysis of these mice highlighted the relevance of non-coding elements in regulating patterns of gene expression. In 2015 he joined the laboratory of Dr. Stuart Orkin at Boston Children’s Hospital, where he trained in hematology, stem cell biology and genomics. In Boston, he used genome editing to explore the role of epigenetic factors in the context of mouse embryonic stem cells, and generated a series of mouse models to study how chromatin modifiers control hematopoiesis, erythropoiesis and the expression of globin genes. His current research is focused on the role of chromatin modifiers and cis-regulatory sequences in pediatric malignancies, supported by grants from Pedals for Pediatrics and the WES Foundation. After receiving a Starting Grant from the ERC, in 2021 he will open his laboratory at the St. Anna Children’s Cancer Research Institute (CCRI) in Vienna, Austria.