Antioxidant improves donated liver survival rate to more than 90 percent.The results of this research have just been published on Liver Transplantation, a journal of the American Association for the Study of Liver Diseases (AASLD), and suggest that the NAC effect on early graft function and survival is higher when suboptimal organs are used. "Liver transplantation is the standard treatment for end-stage liver disease," explains lead author Dr. Francesco D'Amico from Padova University in Italy. "Antioxidants such as NAC could potentially reduce damage to deceased donor livers, improving graft function." Studies have shown that ischemia-reperfusion injury (IFI)—damage to the liver tissue when blood supply returns to the liver after lack of oxygen (ischemia)—often occurs during storage and preservation of donated livers, and impacts early graft function post-transplantation.

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