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Increased Tau Phosphorylation in Transgenic Mice

transgenic miceResearchers investigated tau accumulation and truncation in double transgenic (Tg-FDD-Tau) mice generated by crossing transgenic mice expressing human Danish mutant BRI2 (Tg-FDD) with mice expressing human 4-repeat mutant Tau-P301S (Tg-Tau). An Italian researcher, Bernardino Ghetti, working at the Indiana University School of Medicine, took part to the research. 
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